Product Data Sheet
Syringaresinol
Catalog No. A25908
Syringaresinol is a lignan-type phytochemical that primarily targets anti-inflammatory pathways. It effectively inhibits the NF-κB and AKT signaling pathways in IL-1β-activated mouse chondrocytes, demonstrating significant anti-inflammatory activity. Additionally, Syringaresinol enhances the phosphorylation of AMPK and eNOS while increasing intracellular Ca2+ levels in HUVECs. Its ability to attenuate the progression of osteoarthritis in mouse models of DMM-induced osteoarthritis makes it a valuable reagent for research focused on OA.
Chemical Information
| Catalog Num | A25908 |
|---|---|
| M. Wt | 418.44 |
| Formula | C22H26O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 487-35-4 |
| Synonyms | |
| SMILES | OC1=C(OC)C=C(C2OCC3C2COC3C4=CC(OC)=C(O)C(OC)=C4)C=C1OC |
Biological Activity
| Description | Syringaresinol is a lignan-type phytochemical that primarily targets anti-inflammatory pathways. It effectively inhibits the NF-κB and AKT signaling pathways in IL-1β-activated mouse chondrocytes, demonstrating significant anti-inflammatory activity. Additionally, Syringaresinol enhances the phosphorylation of AMPK and eNOS while increasing intracellular Ca2+ levels in HUVECs. Its ability to attenuate the progression of osteoarthritis in mouse models of DMM-induced osteoarthritis makes it a valuable reagent for research focused on OA. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
