Product Data Sheet
SKI-349
Catalog No. A25932
SKI-349 is a dual-target inhibitor of sphingosine kinase 1 and 2 (SPHK1/2) and modulates microtubule assembly (MDA). This compound exhibits significant anticancer activity, effectively reducing cell viability and invasion in liver cancer. SKI-349 also disrupts the AKT/mTOR signaling pathway, making it a valuable tool for investigating mechanisms of cancer progression and potential therapeutic strategies in oncology research.
Chemical Information
| Catalog Num | A25932 |
|---|---|
| M. Wt | 385.44 |
| Formula | C19H19N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 727686-80-8 |
| Synonyms | |
| SMILES | O=C(C1=C(N)N=C(NC2=CC=C(C=C2)OC)S1)C3=CC=C(C(OC)=C3)OC |
Biological Activity
| Description | SKI-349 is a dual-target inhibitor of sphingosine kinase 1 and 2 (SPHK1/2) and modulates microtubule assembly (MDA). This compound exhibits significant anticancer activity, effectively reducing cell viability and invasion in liver cancer. SKI-349 also disrupts the AKT/mTOR signaling pathway, making it a valuable tool for investigating mechanisms of cancer progression and potential therapeutic strategies in oncology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
