Product Data Sheet
Tizanidine-d4
Catalog No. A25942
Tizanidine-d4 is a deuterated form of Tizanidine, a central α2-adrenoceptor agonist known for its muscle relaxant properties. It primarily acts by inhibiting the release of excitatory amino acids such as glutamate and aspartate in the spinal cord, contributing to skeletal muscle relaxation. Research has demonstrated its ability to inhibit the proliferation, migration, and invasion of lung cancer cells, as well as induce apoptosis through modulation of the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine is clinically applied for managing spasticity associated with conditions like multiple sclerosis, stroke, and spinal cord injury.
Chemical Information
| Catalog Num | A25942 |
|---|---|
| M. Wt | 257.74 |
| Formula | C9H4D4ClN5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1188331-19-2 |
| Synonyms | |
| SMILES | N(C=1C=2C(C=CC1Cl)=NSN2)C=3NC(C(N3)([2H])[2H])([2H])[2H] |
Biological Activity
| Description | Tizanidine-d4 is a deuterated form of Tizanidine, a central α2-adrenoceptor agonist known for its muscle relaxant properties. It primarily acts by inhibiting the release of excitatory amino acids such as glutamate and aspartate in the spinal cord, contributing to skeletal muscle relaxation. Research has demonstrated its ability to inhibit the proliferation, migration, and invasion of lung cancer cells, as well as induce apoptosis through modulation of the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine is clinically applied for managing spasticity associated with conditions like multiple sclerosis, stroke, and spinal cord injury. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
