Product Data Sheet
Tamarixetin
Catalog No. A26004
Tamarixetin, a 4'-O-Methyl Quercetin derivative, serves as a potent inhibitor of the caseinolytic protease P (ClpP) and exhibits significant anti-inflammatory and antioxidant properties. This natural flavonoid effectively inhibits ClpP's hydrolytic activity towards the substrate Suc-LY-AMC with an IC50 of 49.73 μM, making it relevant for research involving Staphylococcus aureus infections. Additionally, Tamarixetin demonstrates the ability to inhibit tumor cell growth, induce apoptosis, and induce cell cycle arrest, while also preventing cardiac hypertrophy through the modulation of NFAT and AKT signaling pathways.
Chemical Information
| Catalog Num | A26004 |
|---|---|
| M. Wt | 316.26 |
| Formula | C16H12O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 603-61-2 |
| Synonyms | 4'-O-Methyl Quercetin |
| SMILES | O=C1C(O)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
Biological Activity
| Description | Tamarixetin, a 4'-O-Methyl Quercetin derivative, serves as a potent inhibitor of the caseinolytic protease P (ClpP) and exhibits significant anti-inflammatory and antioxidant properties. This natural flavonoid effectively inhibits ClpP's hydrolytic activity towards the substrate Suc-LY-AMC with an IC50 of 49.73 μM, making it relevant for research involving Staphylococcus aureus infections. Additionally, Tamarixetin demonstrates the ability to inhibit tumor cell growth, induce apoptosis, and induce cell cycle arrest, while also preventing cardiac hypertrophy through the modulation of NFAT and AKT signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
