Product Data Sheet

Anti-inflammatory agent 22

Catalog No. A26049

main product photo
Anti-inflammatory Agent 22 is an orally active compound targeting the inhibition of lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha (TNF-α) production, demonstrated by an IC50 of 14.6 μM. This agent exhibits preventive effects on lymphedematous tissue by suppressing adipogenesis. Additionally, Anti-inflammatory Agent 22 has been shown to reduce limb lymphedema volume in murine models, making it a valuable tool for research into inflammatory conditions and lymphedema management.
Chemical Information
Catalog NumA26049
M. Wt376.36
FormulaC22H16O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2721484-76-8
Synonyms
SMILESO=C(C1=C(C=C(C=C1)O)OC(C2=CC=CC=C2)=O)/C=C/C3=CC=C(C(O)=C3)O
Biological Activity
DescriptionAnti-inflammatory Agent 22 is an orally active compound targeting the inhibition of lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha (TNF-α) production, demonstrated by an IC50 of 14.6 μM. This agent exhibits preventive effects on lymphedematous tissue by suppressing adipogenesis. Additionally, Anti-inflammatory Agent 22 has been shown to reduce limb lymphedema volume in murine models, making it a valuable tool for research into inflammatory conditions and lymphedema management.
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