Product Data Sheet
Lucidone
Catalog No. A26091
Lucidone is an anti-inflammatory agent derived from the fruit of Lindera erythrocarpa Makino. It effectively inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production in RAW 264.7 mouse macrophages, while also reducing tumor necrosis factor-alpha (TNF-α) secretion and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Additionally, Lucidone prevents the translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and inhibits signaling pathways mediated by c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38MAPK). It also exhibits inhibitory activity against the Dengue virus (DENV), with an EC50 value of 25 μM.
Chemical Information
| Catalog Num | A26091 |
|---|---|
| M. Wt | 256.25 |
| Formula | C15H12O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19956-53-7 |
| Synonyms | |
| SMILES | OC(/C=C/C1=CC=CC=C1)=C2C(C(OC)=CC\2=O)=O |
Biological Activity
| Description | Lucidone is an anti-inflammatory agent derived from the fruit of Lindera erythrocarpa Makino. It effectively inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production in RAW 264.7 mouse macrophages, while also reducing tumor necrosis factor-alpha (TNF-α) secretion and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Additionally, Lucidone prevents the translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and inhibits signaling pathways mediated by c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38MAPK). It also exhibits inhibitory activity against the Dengue virus (DENV), with an EC50 value of 25 μM. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
