Product Data Sheet
Omtriptolide sodium
Catalog No. A26110
Omtriptolide sodium is a derivative of triptolide that acts primarily as an immunosuppressive and anti-inflammatory agent. Its mechanism includes inhibition of T cell activation and proliferation, induction of T cell apoptosis, and suppression of pro-inflammatory cytokines such as IL-2, IFN-γ, and TNF-α through targeting transcription factors like NF-κB. This compound is valuable for research applications focusing on obstructive airway diseases, pulmonary fibrosis, and graft-versus-host disease.
Chemical Information
| Catalog Num | A26110 |
|---|---|
| M. Wt | 482.46 |
| Formula | C24H27NaO9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 195883-09-1 |
| Synonyms | PG 490-88Na |
| SMILES | O=C1OCC2=C1CC[C@@]3(C)[C@@]2([H])C[C@H]4[C@@]5(O4)[C@H](OC(CCC(O[Na])=O)=O)[C@]6(C(C)C)[C@@H](O6)[C@H]7[C@]53O7 |
Biological Activity
| Description | Omtriptolide sodium is a derivative of triptolide that acts primarily as an immunosuppressive and anti-inflammatory agent. Its mechanism includes inhibition of T cell activation and proliferation, induction of T cell apoptosis, and suppression of pro-inflammatory cytokines such as IL-2, IFN-γ, and TNF-α through targeting transcription factors like NF-κB. This compound is valuable for research applications focusing on obstructive airway diseases, pulmonary fibrosis, and graft-versus-host disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
