Product Data Sheet
Eps8 peptide 327
Catalog No. A26122
Eps8 peptide 327 is an HLA-A*2402-restricted peptide antigen derived from the Eps8 protein. It exhibits potent antitumor activity through significant cytotoxicity, effectively inhibiting cancer cell proliferation and inducing apoptosis. Eps8 peptide 327 disrupts the EGFR signaling pathway by modulating downstream signals, including IL-2, TNF-α, and IFN-γ, while also interfering with the Eps8/EGFR interaction. Its efficacy has been demonstrated in HT-29 xenograft mouse models, where it significantly inhibits tumor growth.
Chemical Information
| Catalog Num | A26122 |
|---|---|
| M. Wt | 1176.34 |
| Formula | C56H77N11O15S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1988684-26-9 |
| Synonyms | Eps8(327-335) |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CCCCN)=O)CCC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@H](CCC(O)=O)N)=O)=O)CC(C)C)=O)CC(O)=O)=O)CS)=O |
Biological Activity
| Description | Eps8 peptide 327 is an HLA-A*2402-restricted peptide antigen derived from the Eps8 protein. It exhibits potent antitumor activity through significant cytotoxicity, effectively inhibiting cancer cell proliferation and inducing apoptosis. Eps8 peptide 327 disrupts the EGFR signaling pathway by modulating downstream signals, including IL-2, TNF-α, and IFN-γ, while also interfering with the Eps8/EGFR interaction. Its efficacy has been demonstrated in HT-29 xenograft mouse models, where it significantly inhibits tumor growth. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
