Product Data Sheet

CX-659S

Catalog No. A26135

main product photo
CX-659S is an orally active 5-carboxamide uracil derivative with anti-inflammatory properties. It effectively inhibits lipid peroxidation with an IC50 of 5.9 μM and reduces the infiltration of neutrophils and eosinophils. CX-659S also inhibits the mRNA expression of pro-inflammatory cytokines IL-1β and TNF-α, making it a valuable tool for research on inflammatory conditions.
Chemical Information
Catalog NumA26135
M. Wt464.51
FormulaC25H28N4O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.204980-81-4
Synonyms
SMILESCC1=C2C(CC[C@](C)(O2)C(NC3=C(N(C4=CC=CC=C4)C(N(C3=O)C)=O)N)=O)=C(C(O)=C1C)C
Biological Activity
DescriptionCX-659S is an orally active 5-carboxamide uracil derivative with anti-inflammatory properties. It effectively inhibits lipid peroxidation with an IC50 of 5.9 μM and reduces the infiltration of neutrophils and eosinophils. CX-659S also inhibits the mRNA expression of pro-inflammatory cytokines IL-1β and TNF-α, making it a valuable tool for research on inflammatory conditions.
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