Product Data Sheet
Hecogenin acetate
Catalog No. A26152
Hecogenin acetate is an orally active steroid saponin aglycone that functions primarily as an anti-inflammatory and analgesic agent. It exerts its biological effects by inhibiting the phosphorylation of NF-κB and p38 MAPK signaling pathways, antagonizing TRPA1/TRPM8 channels, and reducing the production of pro-inflammatory cytokines. Additionally, Hecogenin acetate demonstrates neuroprotective and anti-tumor properties, inhibits reactive oxygen species (ROS) production, and downregulates MMP-2 expression. This compound also enhances gastric mucosal defense and promotes ulcer healing while potentially restoring antibiotic sensitivity when used in combination with specific antibiotics.
Chemical Information
| Catalog Num | A26152 |
|---|---|
| M. Wt | 472.66 |
| Formula | C29H44O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 915-35-5 |
| Synonyms | |
| SMILES | [H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@@H](C)[C@@]1([C@]34C)[H])C[C@@]3([H])[C@]5([H])CC[C@@]6([H])C[C@@H](OC(C)=O)CC[C@]6(C)[C@@]5([H])CC4=O |
Biological Activity
| Description | Hecogenin acetate is an orally active steroid saponin aglycone that functions primarily as an anti-inflammatory and analgesic agent. It exerts its biological effects by inhibiting the phosphorylation of NF-κB and p38 MAPK signaling pathways, antagonizing TRPA1/TRPM8 channels, and reducing the production of pro-inflammatory cytokines. Additionally, Hecogenin acetate demonstrates neuroprotective and anti-tumor properties, inhibits reactive oxygen species (ROS) production, and downregulates MMP-2 expression. This compound also enhances gastric mucosal defense and promotes ulcer healing while potentially restoring antibiotic sensitivity when used in combination with specific antibiotics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
