Product Data Sheet
Shizukaol B
Catalog No. A26155
Shizukaol B is an anti-inflammatory agent derived from the lindenane-type dimeric sesquiterpene found in Chloranthus henryi. This compound demonstrates significant inhibitory effects against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells, effectively reducing nitric oxide production and downregulating the expression of pro-inflammatory markers such as iNOS, COX-2, TNF-α, and IL-1β. Shizukaol B is suitable for research applications focused on neuroinflammation and related therapeutic strategies.
Chemical Information
| Catalog Num | A26155 |
|---|---|
| M. Wt | 732.77 |
| Formula | C40H44O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 142279-40-1 |
| Synonyms | |
| SMILES | COC(/C(C)=C1[C@]2([H])[C@@]34[C@](CC5=C2[C@]([C@@]6([H])[C@]5([H])C6)([C@H](C/1=O)O)C)([H])[C@]7([C@@]8([H])[C@]([C@@]9([C@]7([H])CC3=C(COC(CCC(OC/C=C(C(OC9)=O)/C)=O)=O)C(O4)=O)O)([H])C8)C)=O |
Biological Activity
| Description | Shizukaol B is an anti-inflammatory agent derived from the lindenane-type dimeric sesquiterpene found in Chloranthus henryi. This compound demonstrates significant inhibitory effects against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells, effectively reducing nitric oxide production and downregulating the expression of pro-inflammatory markers such as iNOS, COX-2, TNF-α, and IL-1β. Shizukaol B is suitable for research applications focused on neuroinflammation and related therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
