Product Data Sheet

KGYY15

Catalog No. A26185

main product photo
KGYY15 is a CD40-targeting peptide that specifically functions as a CD40 inhibitor, exhibiting a weak inhibition of the CD40-CD40L interaction with an IC50 of over 1 mM. At a concentration of 100 μM, KGYY15 can activate the NF-κB pathway by approximately 33%. This compound is valuable for research applications aimed at understanding the modulation of immune responses and investigating the role of CD40 signaling in various biological contexts.
Chemical Information
Catalog NumA26185
M. Wt1817.12
FormulaC84H129N21O22S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1690215-31-6
SynonymsMouse KGYY15; KGYY15 peptide
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(C)C)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CO)=O)CCCCN)=O)CCSC)=O)[C@@H](C)O)=O)=O)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)C=3C=4C(NC3)=CC=CC4
Biological Activity
DescriptionKGYY15 is a CD40-targeting peptide that specifically functions as a CD40 inhibitor, exhibiting a weak inhibition of the CD40-CD40L interaction with an IC50 of over 1 mM. At a concentration of 100 μM, KGYY15 can activate the NF-κB pathway by approximately 33%. This compound is valuable for research applications aimed at understanding the modulation of immune responses and investigating the role of CD40 signaling in various biological contexts.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.