Product Data Sheet
DRI-C25441
Catalog No. A26203
DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, demonstrating an IC50 value of 0.36 μM. This compound effectively suppresses immune responses triggered by alloantigens and inhibits CD40L-induced activation of the NF-κB signaling pathway. DRI-C25441 is commonly utilized in research related to immune disorders, making it a valuable tool for elucidating mechanisms of immune regulation.
Chemical Information
| Catalog Num | A26203 |
|---|---|
| M. Wt | 531.51 |
| Formula | C31H21N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2101765-83-5 |
| Synonyms | |
| SMILES | O=C(C1=C2C=CC=CC2=C(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C([N+]([O-])=O)C=C5)=O)C=C4)C=C3)=O)C=C1)O |
Biological Activity
| Description | DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, demonstrating an IC50 value of 0.36 μM. This compound effectively suppresses immune responses triggered by alloantigens and inhibits CD40L-induced activation of the NF-κB signaling pathway. DRI-C25441 is commonly utilized in research related to immune disorders, making it a valuable tool for elucidating mechanisms of immune regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
