Product Data Sheet
HDAC8-IN-4
Catalog No. A26383
HDAC8-IN-4 is a selective inhibitor of histone deacetylase 8 (HDAC8), demonstrating an IC50 of 0.15 μM for HDAC8 and 12 μM for HDAC3. This compound is crucial for studies focusing on epigenetic regulation and cancer biology, as it modulates histone acetylation and affects gene expression. HDAC8-IN-4 provides a valuable tool for exploring the therapeutic potential of HDAC inhibition in various diseases.
Chemical Information
| Catalog Num | A26383 |
|---|---|
| M. Wt | 342.44 |
| Formula | C17H14N2O2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1600528-05-9 |
| Synonyms | |
| SMILES | O=C(C1=CC=CC(C2=CSC(CSC3=CC=CC=C3)=N2)=C1)NO |
Biological Activity
| Description | HDAC8-IN-4 is a selective inhibitor of histone deacetylase 8 (HDAC8), demonstrating an IC50 of 0.15 μM for HDAC8 and 12 μM for HDAC3. This compound is crucial for studies focusing on epigenetic regulation and cancer biology, as it modulates histone acetylation and affects gene expression. HDAC8-IN-4 provides a valuable tool for exploring the therapeutic potential of HDAC inhibition in various diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
