2-Hexyl-4-pentynoic acid
Catalog No. A26385

2-Hexyl-4-pentynoic acid serves as an HDAC inhibitor, demonstrating an IC50 value of 13 μM. This compound induces HSP70 expression and promotes histone hyperacetylation, providing neuroprotection against glutamate-induced excitotoxicity in cultured neurons. Additionally, it is utilized in breast carcinoma research and acts as a click chemistry reagent, featuring an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
Chemical Information
| Catalog Num | A26385 |
|---|---|
| M. Wt | 182.26 |
| Formula | C11H18O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 96017-59-3 |
| Synonyms | (±)-2-Hexyl-4-pentynoic acid |
| SMILES | CCCCCCC(CC#C)C(O)=O |
Biological Activity
| Description | 2-Hexyl-4-pentynoic acid serves as an HDAC inhibitor, demonstrating an IC50 value of 13 μM. This compound induces HSP70 expression and promotes histone hyperacetylation, providing neuroprotection against glutamate-induced excitotoxicity in cultured neurons. Additionally, it is utilized in breast carcinoma research and acts as a click chemistry reagent, featuring an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
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Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


