Product Data Sheet
HDAC6-IN-33
Catalog No. A26450
HDAC6-IN-33 is a selective and irreversible inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 193 nM. This compound demonstrates a tight-binding affinity specifically for HDAC6, effectively inhibiting its activity through a two-step slow-binding mechanism. HDAC6-IN-33 is ideal for research applications aimed at studying the role of HDAC6 in various cellular processes and disease states, including neurodegeneration and cancer.
Chemical Information
| Catalog Num | A26450 |
|---|---|
| M. Wt | 303.27 |
| Formula | C14H11F2N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2444302-23-0 |
| Synonyms | |
| SMILES | FC(F)C(O1)=NN=C1C(C=N2)=CN=C2NCC3=CC=CC=C3 |
Biological Activity
| Description | HDAC6-IN-33 is a selective and irreversible inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 193 nM. This compound demonstrates a tight-binding affinity specifically for HDAC6, effectively inhibiting its activity through a two-step slow-binding mechanism. HDAC6-IN-33 is ideal for research applications aimed at studying the role of HDAC6 in various cellular processes and disease states, including neurodegeneration and cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
