Product Data Sheet
HDAC8-IN-8
Catalog No. A26452
HDAC8-IN-8 is a selective inhibitor of HDAC8, exhibiting IC50 values of 23.9 μM for human HDAC8 and 268.2 μM for snail HDAC8. Additionally, it demonstrates inhibitory effects on human HDAC1 and HDAC6, with IC50 values of 12.1 μM and 2.9 μM, respectively. This compound is particularly relevant for research on schistosomiasis and may be useful for studies focused on histone deacetylase modulation in various biological contexts.
Chemical Information
| Catalog Num | A26452 |
|---|---|
| M. Wt | 273.28 |
| Formula | C15H15NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1884231-52-0 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(C(OCC2=CC=CC=C2)=C1)OC)NO |
Biological Activity
| Description | HDAC8-IN-8 is a selective inhibitor of HDAC8, exhibiting IC50 values of 23.9 μM for human HDAC8 and 268.2 μM for snail HDAC8. Additionally, it demonstrates inhibitory effects on human HDAC1 and HDAC6, with IC50 values of 12.1 μM and 2.9 μM, respectively. This compound is particularly relevant for research on schistosomiasis and may be useful for studies focused on histone deacetylase modulation in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
