Product Data Sheet
HDAC1/2-IN-3
Catalog No. A26456
HDAC1/2-IN-3 is a potent inhibitor of histone deacetylases 1 and 2 (HDAC1 and HDAC2), demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively. This compound plays a significant role in modulating gene expression by disrupting histone deacetylation, making it useful in research applications related to cancer biology, neurodegenerative disorders, and epigenetic modifications. Its high selectivity and potency make it a valuable tool for investigating the mechanisms of HDAC-related pathways.
Chemical Information
| Catalog Num | A26456 |
|---|---|
| M. Wt | 431.55 |
| Formula | C24H25N5OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2121516-17-2 |
| Synonyms | |
| SMILES | O=C(C1=CC2=CC=C(NCCN(C)C)C=C2C=N1)NC3=C(N)C=CC(C4=CC=CS4)=C3 |
Biological Activity
| Description | HDAC1/2-IN-3 is a potent inhibitor of histone deacetylases 1 and 2 (HDAC1 and HDAC2), demonstrating IC50 values of 0-5 nM and 5-10 nM, respectively. This compound plays a significant role in modulating gene expression by disrupting histone deacetylation, making it useful in research applications related to cancer biology, neurodegenerative disorders, and epigenetic modifications. Its high selectivity and potency make it a valuable tool for investigating the mechanisms of HDAC-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
