Product Data Sheet

MPT0G413

Catalog No. A26507

main product photo
MPT0G413 is a selective HDAC6 inhibitor with an IC50 of 3.92 nM, demonstrating potent oral bioavailability and the ability to penetrate the blood-brain barrier. This compound effectively reduces tau protein phosphorylation and aggregation, thereby addressing cognitive deficits related to memory and learning. MPT0G413 is suitable for research applications in neurological disorders, including Alzheimer's disease.
Chemical Information
Catalog NumA26507
M. Wt400.43
FormulaC24H20N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2241643-23-0
Synonyms
SMILESO=C(NO)C1=CC=C(CN2C=CC3=C2C=CC(C(C4=CC=C(OC)C=C4)=O)=C3)C=C1
Biological Activity
DescriptionMPT0G413 is a selective HDAC6 inhibitor with an IC50 of 3.92 nM, demonstrating potent oral bioavailability and the ability to penetrate the blood-brain barrier. This compound effectively reduces tau protein phosphorylation and aggregation, thereby addressing cognitive deficits related to memory and learning. MPT0G413 is suitable for research applications in neurological disorders, including Alzheimer's disease.
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