Product Data Sheet

LSD1/HDAC6-IN-2

Catalog No. A26526

main product photo
LSD1/HDAC6-IN-2 is a potent inhibitor targeting LSD1, HDAC6, and MAO-A, with IC50 values of 5 nM, 11 nM, and 5 nM, respectively. It demonstrates significant inhibitory effects on the growth of multiple myeloma cell lines, including MM.1S, MM.1R, and RPMI-8226. This compound is suitable for research applications focused on acute myeloid leukemia and lymphoma, providing insights into potential therapeutic mechanisms.
Chemical Information
Catalog NumA26526
M. Wt443.34
FormulaC21H23BrN4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2982787-50-6
Synonyms
SMILESONC(C(C=C1)=CC=C1CN(N=C2)C=C2CN[C@H]3[C@H](C4=CC=CC=C4)C3)=O.[H]Br
Biological Activity
DescriptionLSD1/HDAC6-IN-2 is a potent inhibitor targeting LSD1, HDAC6, and MAO-A, with IC50 values of 5 nM, 11 nM, and 5 nM, respectively. It demonstrates significant inhibitory effects on the growth of multiple myeloma cell lines, including MM.1S, MM.1R, and RPMI-8226. This compound is suitable for research applications focused on acute myeloid leukemia and lymphoma, providing insights into potential therapeutic mechanisms.
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SHIPPING AND STORAGE
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