Product Data Sheet

PRMT5-IN-21

Catalog No. A26594

main product photo
PRMT5-IN-21 is a potent inhibitor of protein arginine methyltransferase 5 (PRMT5), a crucial enzyme involved in the regulation of gene expression and cellular signaling. This compound effectively suppresses PRMT5 activity, leading to alterations in histone and non-histone protein methylation. PRMT5-IN-21 is valuable for research applications aimed at investigating the role of PRMT5 in various biological processes, including cancer progression and cellular differentiation.
Chemical Information
Catalog NumA26594
M. Wt404.37
FormulaC18H18F2N6O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2922673-38-7
Synonyms
SMILESFC1=C(F)C=CC([C@@H]2[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C(N=CN=C5N)=C5N=C4NCC2)O3)=C1
Biological Activity
DescriptionPRMT5-IN-21 is a potent inhibitor of protein arginine methyltransferase 5 (PRMT5), a crucial enzyme involved in the regulation of gene expression and cellular signaling. This compound effectively suppresses PRMT5 activity, leading to alterations in histone and non-histone protein methylation. PRMT5-IN-21 is valuable for research applications aimed at investigating the role of PRMT5 in various biological processes, including cancer progression and cellular differentiation.
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SHIPPING AND STORAGE
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