Product Data Sheet
DCE_254
Catalog No. A26642
DCE_254 is an EZH2 inhibitor with an IC50 value of 11 μM, demonstrating significant antiproliferative activity against lymphoma cell lines. It interferes with the SAM-mediated methyl transfer process, thereby inhibiting the development of hypermethylation-related cancers, with an IC50 of 10.3 μM. This compound is valuable for research into targeted therapies for cancers influenced by epigenetic modifications.
Chemical Information
| Catalog Num | A26642 |
|---|---|
| M. Wt | 443.48 |
| Formula | C21H17N9OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 673443-80-6 |
| Synonyms | |
| SMILES | O=C1N=C(NC(CSC2=NN=NN2C3=CC=CC=C3)=C1)NC4=NC(C)=C5C=CC=CC5=N4 |
Biological Activity
| Description | DCE_254 is an EZH2 inhibitor with an IC50 value of 11 μM, demonstrating significant antiproliferative activity against lymphoma cell lines. It interferes with the SAM-mediated methyl transfer process, thereby inhibiting the development of hypermethylation-related cancers, with an IC50 of 10.3 μM. This compound is valuable for research into targeted therapies for cancers influenced by epigenetic modifications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
