Product Data Sheet
Antitumor agent-101
Catalog No. A26652
Antitumor agent-101 is a selective covalent inhibitor of the lysine methyltransferases G9a and GLP, exhibiting IC50 values of 8.5 nM and 5.5 nM, respectively. This compound demonstrates significant antitumor efficacy in the PANC-1 xenograft model, making it a valuable tool for studying the role of G9a and GLP in cancer biology. Its mechanism of action provides insights into potential therapeutic strategies for targeting malignant cells through epigenetic modulation.
Chemical Information
| Catalog Num | A26652 |
|---|---|
| M. Wt | 482.62 |
| Formula | C26H38N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2848632-52-8 |
| Synonyms | |
| SMILES | COC1=CC2=C(N=C(N(C)C(C=C)=O)N=C2NC3CCN(C)CC3)C=C1OCCCN4CCCC4 |
Biological Activity
| Description | Antitumor agent-101 is a selective covalent inhibitor of the lysine methyltransferases G9a and GLP, exhibiting IC50 values of 8.5 nM and 5.5 nM, respectively. This compound demonstrates significant antitumor efficacy in the PANC-1 xenograft model, making it a valuable tool for studying the role of G9a and GLP in cancer biology. Its mechanism of action provides insights into potential therapeutic strategies for targeting malignant cells through epigenetic modulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
