Product Data Sheet

PRMT5-IN-29

Catalog No. A26668

main product photo
PRMT5-IN-29 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibiting an IC50 of 1.5 μM. This compound demonstrates significant biological activity and is suitable for advancing research in cancer biology, particularly in the context of targeted therapies. Its potency and oral bioavailability make it a valuable tool for investigating the role of PRMT5 in various malignancies.
Chemical Information
Catalog NumA26668
M. Wt492.74
FormulaC18H20Cl3N5O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2242788-69-6
Synonyms
SMILESO[C@H]([C@@H]1O)[C@@H](O[C@]1([H])[C@](O)(C(C=C2)=CC(Cl)=C2Cl)C)N3C(NC=N/C4=N\OC)=C4N=C3.Cl
Biological Activity
DescriptionPRMT5-IN-29 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), exhibiting an IC50 of 1.5 μM. This compound demonstrates significant biological activity and is suitable for advancing research in cancer biology, particularly in the context of targeted therapies. Its potency and oral bioavailability make it a valuable tool for investigating the role of PRMT5 in various malignancies.
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SHIPPING AND STORAGE
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