Product Data Sheet
CSV0C018875 hydrochloride
Catalog No. A26681
CSV0C018875 hydrochloride is a selective inhibitor of G9a (EHMT2), effectively blocking its enzymatic activity in both enzyme and cell-based assays. This compound demonstrates a lower toxicity profile compared to the known G9a inhibitor BIX-01294, making it a valuable tool for research. CSV0C018875 binds tightly to the active site of G9a, enhancing the compound's inhibitory potency and prolonging its residence time. Its potential for improved ADME (absorption, distribution, metabolism, and excretion) and pharmacodynamic properties positions CSV0C018875 as a promising candidate for further biological studies.
Chemical Information
| Catalog Num | A26681 |
|---|---|
| M. Wt | 349.25 |
| Formula | C18H18Cl2N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 474084-56-5 |
| Synonyms | |
| SMILES | ClC(C=C1)=CC2=C1N=C(C)C=C2NC3=CC=C(OCC)C=C3.Cl |
Biological Activity
| Description | CSV0C018875 hydrochloride is a selective inhibitor of G9a (EHMT2), effectively blocking its enzymatic activity in both enzyme and cell-based assays. This compound demonstrates a lower toxicity profile compared to the known G9a inhibitor BIX-01294, making it a valuable tool for research. CSV0C018875 binds tightly to the active site of G9a, enhancing the compound's inhibitory potency and prolonging its residence time. Its potential for improved ADME (absorption, distribution, metabolism, and excretion) and pharmacodynamic properties positions CSV0C018875 as a promising candidate for further biological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
