Product Data Sheet
EZH2-IN-4
Catalog No. A26695
EZH2-IN-4 is a potent inhibitor of the EZH2 enzyme, exhibiting IC50 values of 0.923 nM for wild type EZH2 and 2.65 nM for mutant EZH2. This compound demonstrates significant anti-cancer activity, making it a valuable tool for research in cancer therapeutics and epigenetic regulation. Its oral bioavailability enhances its potential for in vivo studies targeting EZH2-driven malignancies.
Chemical Information
| Catalog Num | A26695 |
|---|---|
| M. Wt | 511.72 |
| Formula | C29H41N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2088132-99-2 |
| Synonyms | |
| SMILES | CC1=C([C@@H]([C@@]2([H])CC[C@@](N3CC(C3)OC)([H])CC2)C)SC(CCCN4CC5=C(C=C(NC5=O)C)C)=C1C4=O |
Biological Activity
| Description | EZH2-IN-4 is a potent inhibitor of the EZH2 enzyme, exhibiting IC50 values of 0.923 nM for wild type EZH2 and 2.65 nM for mutant EZH2. This compound demonstrates significant anti-cancer activity, making it a valuable tool for research in cancer therapeutics and epigenetic regulation. Its oral bioavailability enhances its potential for in vivo studies targeting EZH2-driven malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
