Product Data Sheet
SAH-EZH2
Catalog No. A26706
SAH-EZH2 is an EZH2/EED interaction inhibitor designed to disrupt the binding between embryonic ectoderm development (EED) and the EZH1/EZH2 complex. This stable α-helical peptide selectively inhibits the trimethylation of histone H3 at lysine 27 (H3K27me3), providing a valuable tool for studying epigenetic regulation. SAH-EZH2 is applicable in research focused on developmental biology and the mechanisms of cancer progression related to the regulation of gene expression by histone modifications.
Chemical Information
| Catalog Num | A26706 |
|---|---|
| M. Wt | 3431.99 |
| Formula | C155H256N48O40 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1453222-26-8 |
| Synonyms | |
| SMILES | C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@]1(C)NC(=O)[C@H](CC(C)C)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCCN)NC(=O)[C@](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(C)=O)=O)CO)=O)CO)=O)CC(N)=O)=O)CCCNC(=N)N)=O)(C)CCCC=CCCC1)[H])CCCNC(=N)N)=O)[C@@H](C)O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(N)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCC3)CCC(N)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCCN)=O)C=4C=5C(NC4)=CC=CC5 |
Biological Activity
| Description | SAH-EZH2 is an EZH2/EED interaction inhibitor designed to disrupt the binding between embryonic ectoderm development (EED) and the EZH1/EZH2 complex. This stable α-helical peptide selectively inhibits the trimethylation of histone H3 at lysine 27 (H3K27me3), providing a valuable tool for studying epigenetic regulation. SAH-EZH2 is applicable in research focused on developmental biology and the mechanisms of cancer progression related to the regulation of gene expression by histone modifications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
