Product Data Sheet
MS023 trihydrochloride
Catalog No. A26718
MS023 trihydrochloride is a potent and selective inhibitor of human type I protein arginine methyltransferases (PRMTs), demonstrating impressive IC50 values of 30 nM for PRMT1, 119 nM for PRMT3, 83 nM for PRMT4, 4 nM for PRMT6, and 5 nM for PRMT8. Its ability to effectively inhibit these enzymes makes it a valuable tool for research into the roles of PRMTs in various biological processes and disease states. This compound is suitable for studies involving cellular signaling, epigenetics, and post-translational modifications.
Chemical Information
| Catalog Num | A26718 |
|---|---|
| M. Wt | 396.78 |
| Formula | C17H28Cl3N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2108631-19-0 |
| Synonyms | |
| SMILES | CC(OC1=CC=C(C=C1)C2=CNC=C2CN(CCN)C)C.Cl.Cl.Cl |
Biological Activity
| Description | MS023 trihydrochloride is a potent and selective inhibitor of human type I protein arginine methyltransferases (PRMTs), demonstrating impressive IC50 values of 30 nM for PRMT1, 119 nM for PRMT3, 83 nM for PRMT4, 4 nM for PRMT6, and 5 nM for PRMT8. Its ability to effectively inhibit these enzymes makes it a valuable tool for research into the roles of PRMTs in various biological processes and disease states. This compound is suitable for studies involving cellular signaling, epigenetics, and post-translational modifications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
