Product Data Sheet
G9a-IN-1
Catalog No. A26721
G9a-IN-1 is a targeted inhibitor of the G9a protein (EHMT2), a nuclear histone lysine methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2), a modification linked to transcriptional repression. By inhibiting G9a, G9a-IN-1 plays a crucial role in unraveling the mechanisms of gene silencing associated with various pathological conditions. This compound is valuable for research in autoimmune disorders and cancer, offering insights into therapeutic strategies for these diseases.
Chemical Information
| Catalog Num | A26721 |
|---|---|
| M. Wt | 462.03 |
| Formula | C24H36ClN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1350752-07-6 |
| Synonyms | |
| SMILES | CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(Cl)=N2)CC1)C |
Biological Activity
| Description | G9a-IN-1 is a targeted inhibitor of the G9a protein (EHMT2), a nuclear histone lysine methyltransferase responsible for the dimethylation of histone H3 at lysine 9 (H3K9me2), a modification linked to transcriptional repression. By inhibiting G9a, G9a-IN-1 plays a crucial role in unraveling the mechanisms of gene silencing associated with various pathological conditions. This compound is valuable for research in autoimmune disorders and cancer, offering insights into therapeutic strategies for these diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
