Product Data Sheet
MAK683 hydrochloride
Catalog No. A26730
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED), targeting the EED protein to disrupt its function. It demonstrates potent inhibitory activity with IC50 values of 59 nM, 89 nM, and 26 nM in EED Alphascreen binding, LC-MS, and ELISA assays, respectively. This compound is primarily utilized in research applications investigating EED's role in gene regulation and cancer biology.
Chemical Information
| Catalog Num | A26730 |
|---|---|
| M. Wt | 412.85 |
| Formula | C20H18ClFN6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2170606-94-5 |
| Synonyms | |
| SMILES | CC1=NC=CC=C1C2=CN=C(NCC3=C4CCOC4=CC=C3F)N5C2=NN=C5.Cl |
Biological Activity
| Description | MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED), targeting the EED protein to disrupt its function. It demonstrates potent inhibitory activity with IC50 values of 59 nM, 89 nM, and 26 nM in EED Alphascreen binding, LC-MS, and ELISA assays, respectively. This compound is primarily utilized in research applications investigating EED's role in gene regulation and cancer biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
