Product Data Sheet
Dot1L-IN-5
Catalog No. A26765
Dot1L-IN-5 is a highly potent inhibitor of the telomeric silencing 1-like protein (DOT1L), exhibiting an IC50 of 0.17 nM. This compound is essential for investigating the role of DOT1L in epigenetic regulation and its implications in various cancers and developmental disorders. It serves as a valuable tool for researchers exploring the therapeutic potential of DOT1L modulation in disease models.
Chemical Information
| Catalog Num | A26765 |
|---|---|
| M. Wt | 592.96 |
| Formula | C23H19ClF2N8O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2565705-03-3 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(N[C@H](C2=NC=CC=C2Cl)C3=C4OC(F)(F)OC4=CC=C3)C(NC5=NC(N)=NC(OC)=N5)=C1)(N)=O |
Biological Activity
| Description | Dot1L-IN-5 is a highly potent inhibitor of the telomeric silencing 1-like protein (DOT1L), exhibiting an IC50 of 0.17 nM. This compound is essential for investigating the role of DOT1L in epigenetic regulation and its implications in various cancers and developmental disorders. It serves as a valuable tool for researchers exploring the therapeutic potential of DOT1L modulation in disease models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
