Product Data Sheet
PRMT5-IN-30
Catalog No. A26772
PRMT5-IN-30 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with an IC50 of 0.33 μM and a Kd of 0.987 μM. This compound demonstrates broad selectivity against various other methyltransferases, making it a valuable tool in biochemical research. PRMT5-IN-30 effectively inhibits the methylation of SmD3 mediated by PRMT5, providing a means to study the functional roles of PRMT5 in cellular processes and disease pathways.
Chemical Information
| Catalog Num | A26772 |
|---|---|
| M. Wt | 371.41 |
| Formula | C18H17N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 330951-01-4 |
| Synonyms | |
| SMILES | C1(SCC(=O)NC2C=CC=CC=2C(OC)=O)NC2C(=CC=C(OC)C=2)N=1 |
Biological Activity
| Description | PRMT5-IN-30 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with an IC50 of 0.33 μM and a Kd of 0.987 μM. This compound demonstrates broad selectivity against various other methyltransferases, making it a valuable tool in biochemical research. PRMT5-IN-30 effectively inhibits the methylation of SmD3 mediated by PRMT5, providing a means to study the functional roles of PRMT5 in cellular processes and disease pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
