Product Data Sheet
UNC2399
Catalog No. A26790
UNC2399, a selective inhibitor of the histone methyltransferase EZH2, exhibits high in vitro potency with an IC50 of 17 nM. This biotinylated compound facilitates the study of EZH2-mediated pathways by enabling researchers to probe histone methylation dynamics. UNC2399 is valuable for investigations into cancer biology, epigenetics, and therapeutic development targeting methyltransferases.
Chemical Information
| Catalog Num | A26790 |
|---|---|
| M. Wt | 1353.66 |
| Formula | C67H104N10O17S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2412791-72-9 |
| Synonyms | |
| SMILES | CCCC(C=C(NC1=O)C)=C1CNC(C2=C3C(N(N=C3)C(C)C)=CC(C4=CN=C(N5CCN(CC5)C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]6[C@]7([H])[C@](NC(N7)=O)([H])CS6)=O)=O)C=C4)=C2)=O |
Biological Activity
| Description | UNC2399, a selective inhibitor of the histone methyltransferase EZH2, exhibits high in vitro potency with an IC50 of 17 nM. This biotinylated compound facilitates the study of EZH2-mediated pathways by enabling researchers to probe histone methylation dynamics. UNC2399 is valuable for investigations into cancer biology, epigenetics, and therapeutic development targeting methyltransferases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
