Product Data Sheet
EPZ011989 trifluoroacetate
Catalog No. A26807
EPZ011989 trifluoroacetate is a selective inhibitor of the enzyme EZH2, exhibiting a Ki value of less than 3 nM. This compound is notable for its ability to effectively inhibit histone methylation, thereby demonstrating significant anti-tumor activity. EPZ011989 trifluoroacetate is applicable in cancer research, providing insights into the role of EZH2 in tumorigenesis. Additionally, it features an alkyne group that facilitates click chemistry applications, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compatible azide-containing molecules.
Chemical Information
| Catalog Num | A26807 |
|---|---|
| M. Wt | 719.83 |
| Formula | C37H52F3N5O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1598383-41-5 |
| Synonyms | |
| SMILES | O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C#CCN3CCOCC3)=CC(N(CC)[C@H]4CC[C@H](N(CCOC)C)CC4)=C2C.O=C(O)C(F)(F)F |
Biological Activity
| Description | EPZ011989 trifluoroacetate is a selective inhibitor of the enzyme EZH2, exhibiting a Ki value of less than 3 nM. This compound is notable for its ability to effectively inhibit histone methylation, thereby demonstrating significant anti-tumor activity. EPZ011989 trifluoroacetate is applicable in cancer research, providing insights into the role of EZH2 in tumorigenesis. Additionally, it features an alkyne group that facilitates click chemistry applications, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compatible azide-containing molecules. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
