Product Data Sheet
MAK683-CH2CH2COOH
Catalog No. A26811
MAK683-CH2CH2COOH is a PROTAC linker that specifically binds to embryonic ectoderm development protein (EED). This compound is instrumental in facilitating targeted protein degradation when paired with a VHL ligand for E3 ubiquitin ligase. Research applications include the development of PROTAC EED degrader-1 and PROTAC EED degrader-2, making it a valuable tool for studying EED-related pathways and therapeutic interventions.
Chemical Information
| Catalog Num | A26811 |
|---|---|
| M. Wt | 448.45 |
| Formula | C23H21FN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2639882-68-9 |
| Synonyms | |
| SMILES | FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(O)=O)C=C4)C5=NN=CN35 |
Biological Activity
| Description | MAK683-CH2CH2COOH is a PROTAC linker that specifically binds to embryonic ectoderm development protein (EED). This compound is instrumental in facilitating targeted protein degradation when paired with a VHL ligand for E3 ubiquitin ligase. Research applications include the development of PROTAC EED degrader-1 and PROTAC EED degrader-2, making it a valuable tool for studying EED-related pathways and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
