Product Data Sheet
Rosiglitazone-d4
Catalog No. A26907
Rosiglitazone-d4 is a deuterated form of Rosiglitazone, a selective agonist of PPARγ with an EC50 of 60 nM and a Kd of 40 nM. In addition to its role as a PPARγ activator, Rosiglitazone also functions as a TRPC5 activator (EC50: 30 μM) and a TRPM3 inhibitor. This compound is valuable for research into obesity, diabetes, cellular senescence, and ovarian cancer. Its stable isotope labeling allows for precise tracking and quantification in various biological studies.
Chemical Information
| Catalog Num | A26907 |
|---|---|
| M. Wt | 361.45 |
| Formula | C18H15D4N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1132641-21-4 |
| Synonyms | BRL 49653-d4 |
| SMILES | O=C(N1)SC(CC2=CC=C(OC([2H])([2H])C([2H])([2H])N(C)C3=NC=CC=C3)C=C2)C1=O |
Biological Activity
| Description | Rosiglitazone-d4 is a deuterated form of Rosiglitazone, a selective agonist of PPARγ with an EC50 of 60 nM and a Kd of 40 nM. In addition to its role as a PPARγ activator, Rosiglitazone also functions as a TRPC5 activator (EC50: 30 μM) and a TRPM3 inhibitor. This compound is valuable for research into obesity, diabetes, cellular senescence, and ovarian cancer. Its stable isotope labeling allows for precise tracking and quantification in various biological studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
