Product Data Sheet
Vildagliptin-d7
Catalog No. A26928
Vildagliptin-d7 is a deuterium-labeled derivative of Vildagliptin, a selective dipeptidyl peptidase IV (DPP-IV) inhibitor with notable potency, exhibiting an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope can be utilized in studies focusing on pharmacokinetics and metabolic profiling of DPP-IV inhibitors, providing insight into their antihyperglycemic effects and oral bioavailability. Vildagliptin-d7 serves as a valuable tool for researchers investigating diabetes therapeutics and related metabolic disorders.
Chemical Information
| Catalog Num | A26928 |
|---|---|
| M. Wt | 310.44 |
| Formula | C17H18D7N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1133208-42-0 |
| Synonyms | LAF237-d7; NVP-LAF 237-d7 |
| SMILES | [2H]C1([2H])C([2H])([2H])C([2H])([2H])[C@@]([2H])(C#N)N1C(CNC2(C3)CC4(O)CC3CC(C4)C2)=O |
Biological Activity
| Description | Vildagliptin-d7 is a deuterium-labeled derivative of Vildagliptin, a selective dipeptidyl peptidase IV (DPP-IV) inhibitor with notable potency, exhibiting an IC50 of 3.5 nM in human Caco-2 cells. This stable isotope can be utilized in studies focusing on pharmacokinetics and metabolic profiling of DPP-IV inhibitors, providing insight into their antihyperglycemic effects and oral bioavailability. Vildagliptin-d7 serves as a valuable tool for researchers investigating diabetes therapeutics and related metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
