Product Data Sheet
Ferfluor-1
Catalog No. A26932
Ferfluor-1 is a potent ferroptosis inhibitor, demonstrating EC50 values of 57 nM in HT108 cells, 75 nM in OS-RC-2 cells, and 2.3 nM in SH-SY5Y neuroblastoma cells. This ratiometric photoluminescent probe is capable of crossing the blood-brain barrier, making it an effective tool for monitoring ferroptotic changes in cellular environments. Ferfluor-1 shows promise in research applications related to neurodegenerative diseases, such as stroke and Parkinson's disease, by mitigating the effects of ferroptosis in in vivo models.
Chemical Information
| Catalog Num | A26932 |
|---|---|
| M. Wt | 288.41 |
| Formula | C15H20N4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3030473-59-4 |
| Synonyms | |
| SMILES | NC1=C(NC2CCCCC2)C=CC(C3=NN=C(C)S3)=C1 |
Biological Activity
| Description | Ferfluor-1 is a potent ferroptosis inhibitor, demonstrating EC50 values of 57 nM in HT108 cells, 75 nM in OS-RC-2 cells, and 2.3 nM in SH-SY5Y neuroblastoma cells. This ratiometric photoluminescent probe is capable of crossing the blood-brain barrier, making it an effective tool for monitoring ferroptotic changes in cellular environments. Ferfluor-1 shows promise in research applications related to neurodegenerative diseases, such as stroke and Parkinson's disease, by mitigating the effects of ferroptosis in in vivo models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
