Product Data Sheet

Ferroptosis inducer-13

Catalog No. A26934

main product photo
Ferroptosis inducer-13 is a 5′-prenylated chalcone derivative that targets and induces ferroptosis in human non-small cell lung cancer (NSCLC) cells by modulating the Nrf2/xCT/GPX4 pathway. This compound demonstrates significant anti-proliferative effects in vitro and effectively inhibits tumor growth in NSCLC mouse models. Ferroptosis inducer-13 serves as a valuable tool for research focused on the mechanisms and treatment of NSCLC.
Chemical Information
Catalog NumA26934
M. Wt337.41
FormulaC21H23NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3085517-19-4
Synonyms
SMILESCOC1=CC(OC)=C(C=C1C(/C=C/C2=NC=CC=C2)=O)C/C=C(C)\C
Biological Activity
DescriptionFerroptosis inducer-13 is a 5′-prenylated chalcone derivative that targets and induces ferroptosis in human non-small cell lung cancer (NSCLC) cells by modulating the Nrf2/xCT/GPX4 pathway. This compound demonstrates significant anti-proliferative effects in vitro and effectively inhibits tumor growth in NSCLC mouse models. Ferroptosis inducer-13 serves as a valuable tool for research focused on the mechanisms and treatment of NSCLC.
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