Product Data Sheet

Ferroptosis inducer-4

Catalog No. A26948

main product photo
Ferroptosis inducer-4 is a potent ferroptosis inducer that introduces terminal double bonds at the sn-2 position of phospholipids. This compound exhibits significant cytotoxicity in HT-1080 cells, with an IC50 of 18 μM, through the generation of lipid peroxides leading to oxidative damage of the cell membrane. Ferroptosis inducer-4 is valuable for research involving the regulation and mechanisms of ferroptosis in various biological contexts.
Chemical Information
Catalog NumA26948
M. Wt617.84
FormulaC33H64NO7P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3055534-10-3
Synonyms
SMILESC[N+](C)(C)CCOP(OC[C@H](OC(CC/C=C/C=C)=O)COCCCCCCCCCCCCCCCCCC)([O-])=O
Biological Activity
DescriptionFerroptosis inducer-4 is a potent ferroptosis inducer that introduces terminal double bonds at the sn-2 position of phospholipids. This compound exhibits significant cytotoxicity in HT-1080 cells, with an IC50 of 18 μM, through the generation of lipid peroxides leading to oxidative damage of the cell membrane. Ferroptosis inducer-4 is valuable for research involving the regulation and mechanisms of ferroptosis in various biological contexts.
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