N6F11
Catalog No. A27039

N6F11 is a selective ferroptosis inducer that targets TRIM25 to promote the degradation of GPX4 in cancer cells while preserving immune cell functionality. This compound triggers HMGB1-dependent antitumor immunity, activating CD8+ T cells and enhancing the immune response against tumors. N6F11 is suitable for research applications focused on cancer therapy and the mechanisms underlying ferroptosis.
Chemical Information
| Catalog Num | A27039 |
|---|---|
| M. Wt | 311.19 |
| Formula | C13H8Cl2N2OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 851398-76-0 |
| Synonyms | |
| SMILES | ClC1=CC=C(C2=CC3=C(C(NC(CCl)=N3)=O)S2)C=C1 |
Biological Activity
| Description | N6F11 is a selective ferroptosis inducer that targets TRIM25 to promote the degradation of GPX4 in cancer cells while preserving immune cell functionality. This compound triggers HMGB1-dependent antitumor immunity, activating CD8+ T cells and enhancing the immune response against tumors. N6F11 is suitable for research applications focused on cancer therapy and the mechanisms underlying ferroptosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


