Product Data Sheet
84-B10
Catalog No. A27044
84-B10 is a potent ferroptosis inhibitor derived from 3-phenylglutaric acid. It effectively inhibits cisplatin-induced tubular ferroptosis, thereby mitigating mitochondrial damage and oxidative stress associated with cisplatin treatment. Consequently, 84-B10 demonstrates protective effects against cisplatin-induced acute kidney injury (AKI), making it a valuable reagent for research on drug-induced nephrotoxicity and ferroptosis-related mechanisms.
Chemical Information
| Catalog Num | A27044 |
|---|---|
| M. Wt | 473.44 |
| Formula | C25H22F3NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 698346-43-9 |
| Synonyms | |
| SMILES | O=C(O)CC(CC(NC1=CC(C(F)(F)F)=CC=C1OC2=CC=C(OC)C=C2)=O)C3=CC=CC=C3 |
Biological Activity
| Description | 84-B10 is a potent ferroptosis inhibitor derived from 3-phenylglutaric acid. It effectively inhibits cisplatin-induced tubular ferroptosis, thereby mitigating mitochondrial damage and oxidative stress associated with cisplatin treatment. Consequently, 84-B10 demonstrates protective effects against cisplatin-induced acute kidney injury (AKI), making it a valuable reagent for research on drug-induced nephrotoxicity and ferroptosis-related mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
