Product Data Sheet

Posaconazole hydrate

Catalog No. A27249

main product photo
Posaconazole hydrate is a broad-spectrum antifungal agent classified as a second-generation triazole derivative. It exerts its activity by inhibiting the enzyme lanosterol 14α-demethylase, crucial for ergosterol synthesis in fungal cell membranes. This compound is particularly effective against various fungal pathogens and is utilized in both in vitro and in vivo studies to explore its efficacy in treating invasive fungal infections.
Chemical Information
Catalog NumA27249
M. Wt718.79
FormulaC37H44F2N8O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1198769-38-8
SynonymsSCH56592 hydrate
SMILESFC1=CC=C([C@@]2(CN3C=NC=N3)C[C@H](COC4=CC=C(N5CCN(C6=CC=C(N7C=NN([C@@H](CC)[C@H](C)O)C7=O)C=C6)CC5)C=C4)CO2)C(F)=C1.O
Biological Activity
DescriptionPosaconazole hydrate is a broad-spectrum antifungal agent classified as a second-generation triazole derivative. It exerts its activity by inhibiting the enzyme lanosterol 14α-demethylase, crucial for ergosterol synthesis in fungal cell membranes. This compound is particularly effective against various fungal pathogens and is utilized in both in vitro and in vivo studies to explore its efficacy in treating invasive fungal infections.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.