Product Data Sheet
E5700
Catalog No. A27275
E5700 is a potent squalene synthase inhibitor, exhibiting an IC50 of 0.49 nM against squalene synthase from Trypanosoma cruzi epimastigotes. This compound demonstrates notable antiparasitic activity, effectively inhibiting the growth of Trypanosoma cruzi and Leishmania amazonensis. Additionally, E5700 impacts the lipid profile and ultrastructure of multi-drug resistant Candida tropicalis strains, making it a valuable tool for research on parasitic infections and antifungal resistance mechanisms.
Chemical Information
| Catalog Num | A27275 |
|---|---|
| M. Wt | 433.54 |
| Formula | C26H31N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 332132-39-5 |
| Synonyms | |
| SMILES | O[C@@]1(CN2CCC1CC2)C#CC3=CC=C(N=C3CC4=CC=CC=C4)N5C[C@H]([C@H](C5)OC)O |
Biological Activity
| Description | E5700 is a potent squalene synthase inhibitor, exhibiting an IC50 of 0.49 nM against squalene synthase from Trypanosoma cruzi epimastigotes. This compound demonstrates notable antiparasitic activity, effectively inhibiting the growth of Trypanosoma cruzi and Leishmania amazonensis. Additionally, E5700 impacts the lipid profile and ultrastructure of multi-drug resistant Candida tropicalis strains, making it a valuable tool for research on parasitic infections and antifungal resistance mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
