Product Data Sheet

SCH 39304

Catalog No. A27301

main product photo
SCH 39304 is an orally active antifungal agent that demonstrates efficacy against systemic candidiasis, aspergillosis, and cryptococcosis, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg in murine models. Pharmacokinetic evaluations reveal a prolonged half-life and significant systemic exposure in both mice and rats. This compound is applicable in anti-infective research, particularly for studying fungal infections and therapeutic interventions.
Chemical Information
Catalog NumA27301
M. Wt331.34
FormulaC13H15F2N3O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.120924-80-3
SynonymsSM-8668
SMILESCS([C@@H](C)[C@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
Biological Activity
DescriptionSCH 39304 is an orally active antifungal agent that demonstrates efficacy against systemic candidiasis, aspergillosis, and cryptococcosis, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg in murine models. Pharmacokinetic evaluations reveal a prolonged half-life and significant systemic exposure in both mice and rats. This compound is applicable in anti-infective research, particularly for studying fungal infections and therapeutic interventions.
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