Product Data Sheet

Inz-1

Catalog No. A27320

main product photo
Inz-1 is a selective inhibitor of mitochondrial cytochrome bc1, exhibiting an IC50 of 8.092 μM in yeast and 45.320 μM in human cells. This compound effectively reverses resistance to Fluconazole and other triazole antifungals in Candida albicans, making it a valuable tool for studying antifungal resistance mechanisms and developing new therapeutic strategies. Researchers can utilize Inz-1 to investigate the role of cytochrome bc1 in fungal pathogenesis and drug resistance.
Chemical Information
Catalog NumA27320
M. Wt266.29
FormulaC16H14N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.897776-15-7
Synonyms
SMILESO=C(OC)CN1N=C(C2=CC=CC=C2)C3=C1C=CC=C3
Biological Activity
DescriptionInz-1 is a selective inhibitor of mitochondrial cytochrome bc1, exhibiting an IC50 of 8.092 μM in yeast and 45.320 μM in human cells. This compound effectively reverses resistance to Fluconazole and other triazole antifungals in Candida albicans, making it a valuable tool for studying antifungal resistance mechanisms and developing new therapeutic strategies. Researchers can utilize Inz-1 to investigate the role of cytochrome bc1 in fungal pathogenesis and drug resistance.
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SHIPPING AND STORAGE
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