Product Data Sheet
SPK-843
Catalog No. A27435
SPK-843 is a potent antifungal agent that demonstrates significant inhibitory activity against Aspergillus fumigatus (MIC 0.5 μg/mL), Aspergillus flavus (MIC 0.25 μg/mL), and Aspergillus niger (MIC 0.0625 μg/mL). This compound exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis, making it valuable for studying therapeutic strategies for fungal infections. SPK-843 can be employed in various research applications related to antifungal drug development and fungal pathogenesis.
Chemical Information
| Catalog Num | A27435 |
|---|---|
| M. Wt | 1282.56 |
| Formula | C67H103N5O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 143483-67-4 |
| Synonyms | SPA-S-753 free base |
| SMILES | O=C([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@]([C@@H](C)CCC(O)CC(C2=CC=C(NC)C=C2)=O)([H])OC3=O)O[C@@](O[C@H](C)[C@@H](O)[C@@H]4NC(CN(C)C)=O)([H])[C@H]4O)([H])O[C@](O)(C[C@H](C[C@H](C[C@H](C[C@H](CC(C[C@H](C3)O)=O)O)O)O)O)C[C@@H]1O)NCCN(C)C |
Biological Activity
| Description | SPK-843 is a potent antifungal agent that demonstrates significant inhibitory activity against Aspergillus fumigatus (MIC 0.5 μg/mL), Aspergillus flavus (MIC 0.25 μg/mL), and Aspergillus niger (MIC 0.0625 μg/mL). This compound exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis, making it valuable for studying therapeutic strategies for fungal infections. SPK-843 can be employed in various research applications related to antifungal drug development and fungal pathogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
