Product Data Sheet
Terbinafine-d3
Catalog No. A27462
Terbinafine-d3 is a deuterium-labeled derivative of the antifungal agent Terbinafine, a potent non-competitive inhibitor of squalene epoxidase with a Ki of 30 nM, effective against Candida species. This compound demonstrates additional antibacterial activity against various Gram-positive and Gram-negative bacteria. Terbinafine-d3 includes an alkyne functional group, making it suitable for click chemistry applications, specifically in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This compound is valuable for research in antifungal therapeutic development and mechanistic studies.
Chemical Information
| Catalog Num | A27462 |
|---|---|
| M. Wt | 294.45 |
| Formula | C21H22D3N |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1133210-36-2 |
| Synonyms | TDT 067-d3 |
| SMILES | CC(C)(C)C#C/C=C/CN(C([2H])([2H])[2H])CC1=CC=CC2=C1C=CC=C2 |
Biological Activity
| Description | Terbinafine-d3 is a deuterium-labeled derivative of the antifungal agent Terbinafine, a potent non-competitive inhibitor of squalene epoxidase with a Ki of 30 nM, effective against Candida species. This compound demonstrates additional antibacterial activity against various Gram-positive and Gram-negative bacteria. Terbinafine-d3 includes an alkyne functional group, making it suitable for click chemistry applications, specifically in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This compound is valuable for research in antifungal therapeutic development and mechanistic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
