Product Data Sheet
Merulidial
Catalog No. A27481
Merulidial is an antibiotic and cytotoxic agent characterized by its sesquiterpene dialdehyde structure. It effectively inhibits the germination of spores and hyphal growth in the wood-rotting basidiomycete Heterobasidion annosum and the saprophytic mold Cladosporium cucumerinum. Additionally, Merulidial demonstrates antibacterial and algicidal properties, along with the ability to inhibit DNA synthesis in ECA cells. Notably, it exhibits potent anticancer activity, with IC50 values of 20 μg/mL for ECA cells and 10 μg/mL for L1210 cells, making it a valuable candidate for further research in cancer and microbial therapeutics.
Chemical Information
| Catalog Num | A27481 |
|---|---|
| M. Wt | 248.32 |
| Formula | C15H20O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 68053-32-7 |
| Synonyms | (-)-Merulidial |
| SMILES | O=C[C@@]12[C@@](C1)([C@H]([C@@]3([H])C(CC(C)(C3)C)=C2C=O)O)C |
Biological Activity
| Description | Merulidial is an antibiotic and cytotoxic agent characterized by its sesquiterpene dialdehyde structure. It effectively inhibits the germination of spores and hyphal growth in the wood-rotting basidiomycete Heterobasidion annosum and the saprophytic mold Cladosporium cucumerinum. Additionally, Merulidial demonstrates antibacterial and algicidal properties, along with the ability to inhibit DNA synthesis in ECA cells. Notably, it exhibits potent anticancer activity, with IC50 values of 20 μg/mL for ECA cells and 10 μg/mL for L1210 cells, making it a valuable candidate for further research in cancer and microbial therapeutics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
