Product Data Sheet

PKR-IN-1

Catalog No. A27576

main product photo
PKR-IN-1 is an inhibitor of pyruvate kinase, demonstrating potent antifungal activity with an EC50 of 0.21 μg/mL against Rhizoctonia solani. Its primary mechanism involves the inhibition of glycolytic metabolism, which is crucial for fungal growth and survival. This compound is valuable for research applications focused on the development of antifungal strategies and the study of metabolic pathways in fungi.
Chemical Information
Catalog NumA27576
M. Wt422.53
FormulaC9HCl5N4OS2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3057531-75-3
Synonyms
SMILESClC1=NSC(C2=CSC(C3=NN=C(C(Cl)(Cl)Cl)O3)=N2)=C1Cl
Biological Activity
DescriptionPKR-IN-1 is an inhibitor of pyruvate kinase, demonstrating potent antifungal activity with an EC50 of 0.21 μg/mL against Rhizoctonia solani. Its primary mechanism involves the inhibition of glycolytic metabolism, which is crucial for fungal growth and survival. This compound is valuable for research applications focused on the development of antifungal strategies and the study of metabolic pathways in fungi.
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